CIMac™ SO3 Analytical Column is a strong cation exchanger based on a monolithic support. This material provides many advantages over conventional stationary phases for the separation of biomacromole ...
H-Bond ADC is the first of a new class of chromatography ligands from BIA Separations that exploits hydrogen bonding as the dominant mode of biomolecule retention. The ligand consists of a terminal se ...
Coupling trypsin directly onto a Convective interaction media (CIM®) monolithic chromatographic support makes it possible to reuse the enzyme for multiple process cycles and to automate hydrolysis pr ...
CIMac PrimaS™ is a new member of BIA’s family of high performance monoliths for analysis and purification of mRNA. Its positive charge gives it some anion exchange behavior but hydrogen bonding ma ...
CIM® SDVB is a polystyrene divinylbenzene monolith used for reversed phase (RP) purification of large biologics. It is used in purification of nucleic acids for size fractionation. In addition to len ...
The stability of QA, DEAE and SO3 CIMac™ Analytical Columns was tested according to the CIP (Cleaning In Place) procedures described in the respective Product Specification Sheets (see Table 1). We ...
CIMac™ pDNA-0.3 Analytical Columns (Pores 1.4 μm) were introduced by BIA Separations d.o.o. in 2010. In the following years they were recognised by the biotechnological and analytical community as ...
Hydrazide-activated (HDZ) columns were proven to be a product of choice for making the most effective immunoaffinity columns. They take advantage of a special hydrazide linkage that binds antibodies t ...
The ligand in CIM® C4 HLD monoliths is a hydrophobic butyl group. RNA binds on the column under hydrophobic conditions. The majority of DNA and short transcripts elute earlier than intact ssRNA, whil ...
The ligand in CIM® PrimaS contains a series of hydrogen donors and hydrogen acceptors, combined with a weak anion exchange character. Its hydrogen bonding ability makes its selectivity entirely disti ...