member: Rok Sekirnik, PhD was appointed as Head of Process Development mRNA/pDNA at the beginning of ... challenges in mRNA manufacturing. BIA Separations has over two decades’ experience in pDNA purification ...
plasmid DNA (pDNA) molecules and AAV particles.
Read full article ...
production of mRNA, starting from plasmid DNA, it is essential to monitor and control every stage of the ... :
- Effective control over linear plasmid upstream and downstream,
- IVT reaction optimization for mRNA ...
optimized for analysis and cGMP production of complex biomolecules ranging from oligonucleotides and plasmid ... DNA (pDNA) to proteins and viruses.
Read full article ...
plasmid DNA (pDNA)with 95% purity. The advantages of this procedure include high plasmid purity and ... virus (HCV) is the pIDKE2 plasmid. The current designed downstream process for the production of ...
Speaker: Rok Sekirnik, Head Process Development for mRNA and pDNAAbstract:
The recently ... including plasmid production, plasmid linearization, an in vitro transcription (IVT) reaction, mRNA ...