ProductsPATfix™ pDNA
Global demand for pDNA production is at an all time high, due to increased need from Gene Therapy ... ramp-up. pDNA, as an enabling product, is critical in production of mRNA, AAV and other therapeutic ...
Global demand for pDNA production is at an all time high, due to increased need from Gene Therapy ... ramp-up. pDNA, as an enabling product, is critical in production of mRNA, AAV and other therapeutic ...
As the demand for plasmid DNA (pDNA) based gene therapy and vaccines increases, large scale, cost ... effective, and reproducible pDNA production will be required. The key to success is a real time in ...
BioProcess International, October 2021 Abstract:Plasmid DNA (pDNA) has become a crucial component in ... grade pDNA has become a production bottleneck, leading to lengthy production delays. There is a ...
excellent choice for fast and exact plasmid DNA (pDNA) monitoring and quantification. Due to high ... supercoiled (sc) pDNA isoforms of a 4.7 kbp large plasmid DNA molecule. The concentration of the pDNA ...
purification, and high resolution separation of DNA plasmid isoforms The CIMac™ pDNA-0.3 ... pDNAWeak anion exchanger Enables fast and reproducible monitoring and quantitation of pDNA ...
downstream processing plasmid DNA (pDNA). Separation of pDNA using traditional particle-based anion ... -exchange supports is usually slow and has a low capacity for pDNA due to steric exclusion effects. Due ...
Plasmid DNA (pDNA) as a pharmaceutical product has stringent requirements of purity and efficacy ... butyl-modified chromatographic monolith (CIMmultus™ C4 HLD, part of CIMmultus™ HiP² Plasmid Process ...
Since plasmid DNA (pDNA) as a pharmaceutical product has stringent requirements of purity and ... ligand density butyl-modified (C4 HLD) monolithic support is currently used in a polishing step of a pDNA ...
Application of plasmid DNA for gene therapy and vaccination has gained huge interest in last two ... decades. Topological homogeneity and impurity content are crucial for therapeutic usage of pDNA. Major ...
(pDNA) quality, with ability to separate pDNA isoforms (sc, oc, lin, multimer). Plasmid linearization ... Agarose gel electrophoresis (AGE) analysis is an important method for monitoring of plasmid DNA ...