For AAV application, we are developing PrimaS column with stricter release criteria for higher ... reproducibility of AAV empty-full separation. Until this product is finalized, PrimaS for AAV is only ...
CIMac™ AAV full/empty-0.1 Analytical Columns are designed for fast and reproducible HPLC monitoring ... , aggregated and damaged particles from genome containing virus vectors. CIMac™ AAV full/empty-01 ...
column for performing separation of empty and full capsids.CIMac PrimaS™ (AAV) beta employs a new ... .CIMac PrimaS™ (AAV) beta can also be eluted with salt gradients and often provides better resolution ...
CIMac™ AAV full/empty analytical column to estimate the ratio of empty and full AAV particles based on ... capsid containing single stranded DNA. CIMac™ AAV column consisted of a strong anion exchanger with QA ...
scattering in combination with three analytical columns traded as CIMac ™ AAV Empty/Full, CIMac PrimaS ... ™ (AAV) - Beta, and CIMac ™ PrimaT - Beta by BIA Separations Sartorius. The separation columns were ...
classes. In this study we use filtered lysate containing AAV 8 to demonstrate the ability of a ... strong cation exchange monolith (CIMac ™ SO3-0.1) coupled with multiple monitors to enable high ...
Removal of empty capsids is a particular goal of AAV purification. Multimodal PrimaT ligand offers ... clearance of contaminating DNA. PrimaT works for different AAV serotypes - for example AAV 2/8 and AAV ...
capsids was achieved on the CIMac AAV full/empty analytical column (strong anion exchanger, QA quaternary ... AAV vector lots are generally a heterogeneous mixture of empty particles (i e do not contain DNA ...
AAV, and other therapeutic vectors How the PATfix™ pDNA platform using CIMac™ pDNA column offers ...
ramp-up. pDNA, as an enabling product, is critical in production of mRNA, AAV and other therapeutic ... SOP pFix5 sc/oc pDNA standard for 20x calibrations Set of 5 CIMac™ pDNA columns ...