As the demand for plasmid DNA (pDNA) based gene therapy and vaccines increases, large scale, cost ... effective, and reproducible pDNA production will be required. The key to success is a real time in ...
Plasmid DNA (pDNA) as a pharmaceutical product has stringent requirements of purity and efficacy ... butyl-modified chromatographic monolith (CIMmultus™ C4 HLD, part of CIMmultus™ HiP² Plasmid Process ...
. In pharmaceutical applications, requirements for purity and efficacy of plasmid DNA (pDNA) as a ... therapeutic product are stringent. The separation of linear, supercoiled (sc) and open-circular (oc) pDNA ...