EventsRNA Therapeutics
Head Process development for mRNA and pDNA Abstract: In vitro-transcribed messenger RNA-based ... mRNA: Removing Bottlenecks in Process Development and Manufacturing Speaker: Rok Sekirnik ...
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PostersCIMmultus™ Oligo dT affinity column based extraction of mRNA from IVT mixtures
The increasing demand for messenger RNA (mRNA) as a therapeutic product requires larger production ... poly-adenylated mRNA using affinity chromatography on CIMmultus™ Oligo dT column is presented. The ...
WebinarsPurification of single single-stranded mRNA: The toolbox for the next generation
Messenger RNA is poised to become a major contributor in the fields of gene therapy and vaccines ... features and challenges. Some of those challenges are inherent to mRNA. Others are byproducts of RNA ...
PostersProduction scale up of SDVB monolithic columns for the purification of mRNA molecules
Messenger RNA (mRNA) is becoming a major contributor in the fields of gene therapy and vaccines ... separation of mRNA, enabling large-scale production of this molecule. This study demonstrates the ...
EventsmRNA-Based Therapeutics Summit
Head Process development for mRNA and pDNA Abstract: In vitro-transcribed messenger RNA-based ... mRNA: Removing Bottlenecks in Process Development and Manufacturing Speaker: Rok Sekirnik ...
WebinarsmRNA: Removing Bottlenecks in Process Development and Manufacturing
of Process development for mRNA and pDNA Abstract: In vitro-transcribed messenger RNA-based ... Event: mRNA-Based Therapeutics Summit Europe Date: January 2022 Presenter: Rok Sekirnik, Head ...
PublicationsIncreasing Dynamic Binding Capacity of Oligo(dT) for mRNA Purification: Experimental Results Using CIM 96-Well Plates
Abstract:Messenger RNA (mRNA) emerged as a powerful therapeutic tool for treatments in gene therapy ... , oncology, and infectious diseases, as recently demonstrated by vaccines against Covid-19. mRNA is ...
PublicationsHigh Recovery Chromatographic Purification of mRNA at Room Temperature and Neutral pH
Messenger RNA (mRNA) is becoming an increasingly important therapeutic modality due to its potential for ... fast development and platform production. New emerging RNA modalities, such as circular RNA, drive ...
PublicationseBook: PATfix™ pDNA analytical platform for rapid monitoring and optimization of pDNA production process
the production of next generation therapeutics such as messenger RNA (mRNA) and viral vectors. As ...
PublicationsPurification of linearized template plasmid DNA decreases double-stranded RNA formation during IVT reaction
Molecular Biosciences, volume 10, 2023. After the COVID-19 pandemic, messenger RNA (mRNA) has ... revolutionized traditional vaccine manufacturing. With the increasing number of RNA-based therapeutics ...