CIMac Oligo dT18

The CIMac Oligo dT18 Analytical Columns are designed for fast and efficient HPLC monitoring and quantitation of messenger RNA (mRNA) with a poly-adenylated tail. Utilizing oligo dT ligands covalently bound to a solid support, these columns enable hybridization to the poly-adenylated tail present on most eukaryotic mRNAs or synthesized during in vitro transcription (IVT). Ideal for process analytical technology (PAT), they facilitate rapid and efficient capture and purification of mRNA from various sources, effectively removing impurities and ensuring high yield and purity.

Key Features:

• Oligo dT ligand covalently bound to a solid support for efficient mRNA capture
• Simplified workflow with direct application of IVT material to the column without buffer exchange
• High yield and purity with laminar flow minimizing shear stress, preserving mRNA integrity