Cell 2024

Join our presentation

Speaker: Ales Strancar, Managing Director at Sartorius BIA Separations

Date and Time: Thursday, November 7, 2024 | 3:10 PM (Track 5: Strategies for Gene Therapy Manufacturing & Production)

Title: Next Generation AAV Manufacturing Process

Abstract:

Replacing affinity capture with a strong anion exchanger offers a 30% higher recovery, resulting in a 30% increase in doses available for clinical use. The new process also improves the removal of empty and partial AAV capsids, as well as infectious viruses and endotoxins. Additionally, the PATfix Switcher provides insight into the upstream processing (USP) black box, enabling the optimization of full capsid production.

Stop by our booth (#1&2) 

Wednesday, November 6 | 11:35 AM

Accelerating Product Development by using Advanced Analytical Solutions

A 2-hour workshop

Presenters:
Andreja Gramc Livk, Head of Process Analytics, Sartorius BIA Separations
Nejc Pavlin, Process Analytics Development Manager, Sartorius BIA Separations

Tentative Agenda:

1. Introduction and Welcome (5 minutes)

• Brief introduction to the workshop and its objectives.
• Overview of the importance of advanced analytical tools in cell and gene therapy.
• Introduction of the speakers and their expertise.

2. Session 1: The Need for Advanced Analytical Tools in Cell & Gene Therapy (20 minutes)

• Current challenges in cell and gene therapy analytics.
• Placement of analytical platforms for process development of AAV |  pDNA  |  mRNA  |  LNP
• Overview of the chromatographic analytical system and its unique features.

3. Session 2: Real-World Applications and Case Studies (25 minutes)

• Detailed case studies demonstrating the system’s application in cell and gene therapy.
• Data and results showcasing the system’s performance and benefits.

4. Break and Networking (10 minutes)

• Opportunity for attendees to network and discuss the content presented.
• Light refreshments provided.

5. Session 3: PATfix LNP Switcher | Live Demonstration and Hands-On Experience (30 minutes)

• Live demonstration of the LNP Switcher analytical system.
• Step-by-step walkthrough of the system’s operation.
• Interactive Q&A session with the audience.

6. Session 4: Panel Discussion and Q&A (25 minutes)

• Open floor for questions from the audience.
• Panel discussion on the future of analytical systems in cell and gene therapy.
• Insights on upcoming trends and innovations in the field.

7. Closing Remarks and Call to Action (5 minutes)

• Summary of key takeaways from the workshop.
• Information on how attendees can learn more or get involved.
• Invitation to visit the company’s booth or schedule a one-on-one meeting for further discussion.

About the event

Cell 2024 has expanded into a three-day Congress, offering exclusive C- & Executive Level panel discussions on crucial topics within the CGT field. Additionally, we are thrilled to introduce our brand-new Innovation & Collaboration track, designed to spotlight pioneering presentations from emerging biotechs and spin-off companies.

Location: London, UK