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Application NotesPATfix® mRNA Analytical Methods for Process Development and Production

Robust and precise chromatographic analytical methods are key for efficient development of mRNA ... chemistries, are embedded in a ready-to-use PATfix™ mRNA analytical platform to support mRNA process development and product quantification and characterization. ...

Application NotesScreening binding conditions on CIM® Oligo dT 96-well plate to optimize dynamic binding capacity

Affinity-based chromatographic isolation of mRNA is robust and simple, lending itself as a useful ... industrial platform. mRNA constructs contain a 3’ polyA tail to increase stability in vivo, thereby ...

Application NotesOligo dT immobilization on CIMmic CDI-0.1 column

(mRNA) as a therapeutic product requires larger production scales, and in turn more efficient ... is present on most eukaryotic mRNAs, or synthetised onto the molecule during IVT, while other ...