Seminars & Webinars
2020
Presenter: Aleš Štrancar
Date: October 27, 2020
Gene Therapy for Rare Disorders Europe 2020 (digital event)
Bullet points:
- Buffer optimisation and proper column ligand selection (CIM QA, CIM PrimaS or new CIM EF) allows for >90% full capsid production
- Introduction of Specimen allows for production columns checking before use
- Using ultracentrifuge with set of HPLC detectors allows for prompt orthogonal verification of the full capsid purity
Attachments
Presenter: Aleš Štrancar
Date: August 27, 2020
2nd Bacteriophage Therapy Summit 2020 (digital event)
Many of the most compelling applications of bacteriophages involve human therapy, some pertinent to gene therapy, others to antibiotic replacement. These applications require removal of host cell contaminants to acceptable levels, including proteins, DNA and, most of all, endotoxins. This presentation will highlight some of the challenges with effective endotoxin removal, and introduce a new chromatography product that achieves good endotoxin removal while maintaining high recovery of bacteriophage. Case study data will be shared documenting the performance of a platform purification method that enable complete bacteriophage purification within a single shift. Fast analytical methods for qualification of raw materials and tracking phages through the steps of a purification process will also be presented.
Attachments
2019
Presenter: Ales Strancar
Date: 20th of November 2019
Place: Boston, MA (Gene Therapy Analytical Development Summit)
Attachments
Presenter: Ales Strancar
Date: 19th of June 2019
Place: Biomanufacturing Training & Education Center (BTEC) in North Carolina