Exosome purification with CIMmultus™ EV-1 Advanced Composite Column

Exosomes fulfill a critical role as communicators among cells, with targeting and message content depending on their surface receptors and payload. This makes them obvious candidates for an extensive range of diagnostic, therapeutic applications and a need for a fast, robust and scalable purification procedure.

CIMmultus™ monolithic columns are designed to meet the special fractionation needs of very large biologics like exosomes.

We show examples of exosome purification from cell culture with CORNERSTONE Exosome Process Development Pack and analysis of exosomal vesicle populations by Image stream flow cytometry.