Sartorius BIA Separations
- Oligo dT (deoxythymine)
- Oligo dT ligands covalently bound to a solid support
- Hybridises to the poly-adenylated tail which is present on most eukaryotic mRNAs, or synthetised onto the molecule during IVT
- Primarily intended for fast and efficient capture and purification of mRNA with a poly-adenylated tail, from various sources
- Can selectively remove impurities from the sample and is a convenient approach for initial purification of mRNA
Oligo dT18 is available with 6-Carbon and 12-Carbon linker. Performance is comparable, but can be further evaluated if desired. The starting column of choice is with 12-Carbon linker.