Sartorius BIA Separations
OH (hydroxy)
- Uncharged (neutral) ligand
- Working range, pH 2–10
- Retains very large solutes (virus particles, VLP, vesicles) in the presence of precipitating salts or polyethylene glycol, and elutes them with high resolution in order of increasing size
- Elution with descending salt or polyethylene glycol
- Sanitizable with 1 M NaOH
CIMac™ Analytical Columns are intended for fast and reproducible HPLC monitoring and quantitation of large proteins, plasmid DNA, viruses, virus-like particles, and phages. They were primarily designed for the in-process and final control of various samples at different stages of the purification process. They can be operated at high volumetric flow rates (from 1 to 20 column volumes/min); therefore, the information about the product quantity and purity can be obtained within a few minutes. CIMac™ Analytical Columns are fast and reliable PAT tools, providing:
- Rapid, high resolution analysis, achieved in minutes
- Flow independent separation
- High sensitivity and reproducibility