SDVB (polystyrene divinylbenzene)

The strongly hydrophobic structure of polystyrene divinylbenzene (SDVB) enables reversed phase purification of nucleic acids and other biomolecules. It is characterised by:

  • Strongly hydrophobic surface for RP or ion-pair RP chromatography
  • Enables size separation and purification of nucleic acids (DNA, RNA)
  • High caustic stability, flow independent performance, ease of scalability
  • Available as CIMac analytical column for HPLC analytics

Note: For optimal performance, exposure of SDVB monolith to aqueous media should be minimized, and mobile phases should contain organic modifiers.


  • Screening of chromatographic conditions (example binding, washing, elution conditions)
  • High throughput reversed phase purification of nucleic acids and other biomolecules


Filter Products

Channel size:
ImageProduct nameCatalog no.VolumeChannel sizeProduct sheetInquiry
CIM® SDVB 0.05 mL Monolithic 96-Well Plate (2 μm)BIA-122.9001-20.05 mL2 μm
CIM® SDVB 1.0 mL Monolithic 24-Well Plate (2 μm)BIA-124.9001-21 mL2 μm
CIM® SDVB 0.2 mL Monolithic 96-Well Plate (2 μm)BIA-120.9001-20.2 mL2 μm

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