Sartorius BIA Separations
SDVB (polystyrene divinylbenzene)
The strongly hydrophobic structure of polystyrene divinylbenzene (SDVB) enables reversed phase purification of nucleic acids and other biomolecules. It is characterised by:
- Strongly hydrophobic surface for RP or ion-pair RP chromatography
- Enables size separation and purification of nucleic acids (DNA, RNA)
- High caustic stability, flow independent performance, ease of scalability
- Available as CIMac analytical column for HPLC analytics
Note: For optimal performance, exposure of SDVB monolith to aqueous media should be minimized, and mobile phases should contain organic modifiers.
Applications:
- Screening of chromatographic conditions (example binding, washing, elution conditions)
- High throughput reversed phase purification of nucleic acids and other biomolecules
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