Sartorius BIA Separations
- Oligo dT ligands covalently bound to a solid support
- Hybridises to the poly-adenylated tail which is present on most eukaryotic mRNAs, or synthetised onto the molecule during IVT
- Primarily intended for fast and efficient capture and purification of mRNA with a poly-adenylated tail, from various sources
- Can selectively remove impurities from the sample and is a convenient approach for initial purification of mRNA
Applications:
- Screening of chromatographic conditions (example binding, washing, elution conditions)
- High throughput of mRNA purification
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