Sartorius BIA Separations
OH (Hydroxy) – HIC
- Uncharged (neutral) ligand
- Working range, pH 2–10
- Retains very large solutes (virus particles, VLP, vesicles) in the presence of precipitating salts or polyethylene glycol, and elutes them with high resolution in order of increasing size
- Elution with descending salt or polyethylene glycol
- Sanitizable with 1 M NaOH
Applications:
- Screening of chromatographic conditions (example binding, washing, elution conditions)
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