FastFacts: mRNA Manufacturing Platform Using CIMmultus® and CIMac Technology for High Recovery of Stable mRNA Drug Substance with Rapid HPLC Analytics

Watch the video or read the poster to learn:

  • Non-affinity chromatography with PrimaS provides purification for IVT processes with co-transcriptional polyadenylation
  • The Sartorius mRNA purification toolbox provides a scalable chromatographic solution for commercial manufacturing of mRNA therapeutics
  • CIMac analytical HPLC columns can resolve individual IVT reaction components in minutes, resolving the analytical bottleneck in optimization of IVT reaction conditions
  • Rapid HPLC analytics can improve in-process and quality control of the mRNA production process

Rok Sekirnik, Head Process development for mRNA and pDNA, Sartorius BIA Separations

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