Join Nejc Pavlin, as he delves into the innovative chromatography solutions for analysing lipid nanoparticles.
Speaker:
Nejc Pavlin, Project Manager, Process Analytics Development, Sartorius BIA Separation
Watch the webinar to:
- Explore the use of chromatography in analyzing lipid nanoparticle-based therapeutics.
- Gain insights into drug product characterization beyond just size and encapsulation efficiency.
- Discover innovative analysis techniques that eliminate the need for sample pre-treatment when examining separate components.
Abstract:
Lipid nanoparticles (LNPs) have emerged as powerful drug delivery systems capable of encapsulating a wide range of nucleic acid payloads. They offer key advantages such as protection of RNA from degradation, enhanced cellular uptake, and controlled release—making them highly promising for therapeutic applications, including mRNA vaccines and gene therapies. Accurate and robust analytical methods are essential to ensure the quality, efficacy, and safety of LNP-based drug products. Liquid chromatography serves as a powerful tool to assess these properties, offering high-resolution insights into both nucleic acid and lipid components.
