2025
Join us for an engaging webinar hosted by Sartorius BIA Separations, where we introduce the LNP Analytical Platform—a specialized chromatographic tool crafted for in-depth characterization of RNA-LNP drug products. Through case studies, you’ll discover how the PATfix system is applied at various stages of mRNA vaccine production.
Key Takeaways:
- Explore the use of chromatography in analyzing lipid nanoparticle-based therapeutics.
- Gain insights into drug product characterization beyond just size and encapsulation efficiency.
- Discover innovative analysis techniques that eliminate the need for sample pre-treatment when examining separate components.
Speaker:
Nejc Pavlin, PhD, Project Manager, Process Analytics Development at Sartorius BIA Separations
Abstract:
Lipid nanoparticles (LNPs) have emerged as powerful drug delivery systems capable of encapsulating a wide range of nucleic acid payloads. They offer key advantages such as protection of RNA from degradation, enhanced cellular uptake, and controlled release—making them highly promising for therapeutic applications, including mRNA vaccines and gene therapies.
Accurate and robust analytical methods are essential to ensure the quality, efficacy, and safety of LNP-based drug products. Liquid chromatography serves as a powerful tool to assess these properties, offering high-resolution insights into both nucleic acid and lipid components.
