Screening

Chromatographic Screening Solutions for Efficient Bioprocess Development:

CIM® Multi-well Plates

High-throughput condition screening in 24- and 96-well format

With automation compatible CIM® Multi-Well Plates you can screen multiple chromatographic conditions or prepare multiple small samples at once. Wide range of chemistries and in 24-well or 96-well plate format are here to make your mRNA, pDNA, LNP, AAV, LV and other viral vector processes our priority. Matching chromatographic characteristics of monoliths as in our preparative line of column enables you a straightforward transfer from one scale to another.  

 

CIM® Octa Columns

Parallel screening with 8-column strips for automated systems

Make parallel screening of chromatographic conditions for your AAV, LV, mRNA, pDNA, LNP or other large biomolecule easy. Designed for automated robotic liquid handlers CIM® Octa columns can power through your multiple parameters in a single sweep. 8 columns on a strip, with the capacity to arrange up to 12 strips on a 96-array plate can assist you in quickly generating the data needed to transfer your process to preparative line of monoliths. Whether you are optimizing conditions or exploring new methodologies, the CIM Octa columns provide the adaptability you need. 

 

CIMmic® Immobilization Screening

Custom affinity screening and enzymatic reactor development

Easily create your custom monolith with 3 different CIMmic pre-activated surface chemistries. Use the advantage of monolith design and small volume to make your own affinity column or enzymatic reactor. CIMmic’s can be operated via syringe, lowpressure pump, or HPLC making them suitable for your immobilization screening and protocol optimization. 

Monolith technology delivers superior mass transfer, low backpressure, and high binding capacity, critical for efficient purification of large biomolecules. Our screening formats mirror the performance of our preparative CIMmultus® monolithic columns, ensuring predictable scale-up and consistent results.

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