3rd LNP Characterization & Analytical Development Summit

Presentation synopsis:

• The presentation introduces innovative chromatographic techniques that use Convective Interaction Media (CIM) monolithic columns for detailed analysis of various LNP formulations like CAR-T cell therapies, CRISPR gene editing, and combination vaccines
• The highlighted approach is an advanced 2D chromatography platform that enables characterization of various LNP-based therapeutics, including assessments of quality attributes such as encapsulation efficiency, RNA integrity, and the detection of nucleic-acid lipid impurities
• Additionally, an analysis of coated LNP formulations is shown to assess ligand density

Don’t miss our poster:

• End-To-End Process for Improved Purity, Combined With Innovative Analytics of LNP-Based Therapeutics presented by Nejc Pavlin