The PATfix® AAV Switcher Platform is an advanced analytical solution that leverages established liquid chromatography techniques to provide a comprehensive analysis and control of USP samples.
It enables accurate estimation of the final viral vector quality, including critical parameters such as the percentage of full AAV capsids. Designed for easy integration into routine laboratory workflows, the PATfix AAV Switcher Platform reduces sample preparation steps, minimizes variability, and lowers the risk of errors, thus supporting reliable and efficient upstream process monitoring. Unlike some other complementary analytical methods for USP monitoring, which combine multiple techniques (e.g., ELISA, PCR) to estimate the full capsids or require pre-purified samples to minimize matrix effects, the PATfix AAV Switcher Platform allows for faster throughput analysis and quicker USP optimization.
