Development of Full Capsid Enrichment Step in AAV Purification Process with CIMmultus® PrimaT Monolith
CIMmultus PrimaT demonstrates efficient separation of empty and full AAV capsids even from AAV9 serotype. In this Genethon case study, possible impact of following parameters on full AAV9 enrichment were explored: viral loading amount, residence time, salt type, elution mode, inter and intra batches, scale up and robustness of the process for another serotype.
*This poster was presented by Genethon at MSS2024.
