Leaders in monolith chromatography


Ion Exchange

DEAE (diethylamine) is a weak type of anion exchange group, fully charged between pH 3-9. It selectively binds biomolecules with a predominant negative charge over a working pH range of 3-9. DEAE is a versatile chemistry for various applications in downstream processing, having clear assets during capture step. Monolithic DEAE has particularly proven of value for purification and concentration of viruses, VLPs, and large proteins. It has a compelling high-binding capacity for pDNA and is your chemistry of choice for any kind of pDNA purification. Due to the difference in chemistry of QA (strong anion exchanger) and DEAE (weak anion exchanger), selectivities for a certain molecule are different.