Process Analytical Technology
Molecular therapies are providing new hope to patients with genetic diseases, but they also present new challenges for process development and control. At BIA Separations, we are passionate about providing the best solutions for virus and plasmid DNA purification, as well as analysis and control of both upstream and downstream bioprocesses.
Using our CIMac™ analytical columns, the PATfix HPLC system gives you “at-line” analysis for the control of impurities and critical quality components using HPLC fingerprinting. Featuring bio-inert ceramic pump heads, and flow rates up to 10 mL per minute, PATfix is designed to manage the analytical parameters for a wide range of biological products. A highly sensitive, multi-wavelength UV detector, as well as a fluorescence detector, capture component peaks, even with the steepest gradients.
PATfix is powered by inCyght® bioprocess software which offers an elaborate, yet user-friendly toolbox for the automated analysis of chromatographic data sets, while providing rapid feedback to help you make critical process control decisions. PATfix delivers the speed, power, and flexibility required for process analytical technology (PAT) in the development of molecular therapies.