Products for immobilization screening
CIMmic™ is cost-efficient line of small monolithic columns with pre-activated surface used as a basis for preparation of custom-made chromatographic columns, diagnostic tools as well as enzyme reactors by a covalent coupling of numerous ligands, such as proteins, nucleic acids, peptides etc. The covalent nature of the bond between the ligand and matrix reduces leaching and improves stability and reusability. CIMmic™ combines the advantages of the CIM® stationary phase (distinguished by large flow-through channels, designed for working with large proteins, viruses, VLPs and pDNA) with a flexible design and the possibility to operate manually with syringe, low pressure pumps or HPLC system. CIMmic™ small bed volume (0.1 mL) is particularly suitable for early screening purposes and optimizing immobilization protocols due to economic usage of often expensive ligands. CIMmic™ columns are available with 2μm channels.