Cell and Gene Therapy Insights Webinar

Accelerate your AAV process development with a new-wave analytical tool

Speaker: Andreja Gramc Livk, Sartorius BIA Separations
Date & Time: July 26, 08:00 PDT | 11:00 EDT | 16:00 BST | 17:00 CEST

Abstract:

Adeno-associated viruses (AAVs) are widely used vectors for gene therapies, mainly due to their favorable safety profile and high transduction efficiency to various target tissues. With increasing demand for faster process development of advanced therapies using AAVs, rapid at-line analytical chromatographic solutions are becoming indispensable.

PATfix™ analytical system with multiple detectors seamlessly delivers coherent process information, considerably speeding up process development and enabling a fast-paced delivery of the product to the market.

Analytical methods embedded in the PATfix™ system enable at-line monitoring of common product- and process-related impurities and provide a critical platform for the rapid development and characterization of AAV-based gene therapy vectors.

• Analytical platform to support process development and product QC
• Analytical method for E/F separation
• Monitoring impurities and final product analysis
• Analytical platform with multiple detector setup

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