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mRNA Applications in Discovery & Development

At-line mRNA synthesis & purification tracking using complementary HPLC analytics

Speaker: Blaz Bakalar, Product Manager PATfix platform

Date & Time: June 28, 2022 I 10 am ET

Key message:

Optimizing the IVT reaction for high mRNA yield requires construct-specific considerations. At first the IVT reaction might seem simple compared to cell derived samples, containing mostly nucleotides and their by-products. Effective mRNA process development needs to separate & identify these species, so they can be tracked & removed. The PATfix mRNA analytical platform is specifically designed to tackle these challenges.

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