HPLC analytical platform for monitoring mRNA production process
Event: Cell and Gene Therapy Insights webinar
Date: June 7, 2022
Presenter: Nejc Pavlin
Pre-developed and validated HPLC analytical methods using different column chemistries enable:
- Effective control over linear plasmid upstream and downstream,
- IVT reaction optimization for mRNA synthesis,
- Control of yield, purity and downstream process of mRNA,
- mRNA formulation and stability analysis,
- Scale-up optimization.
In this webinar, will discuss a robust analytical tool PATfix™ HPLC platform, and its specific methods for pDNA and mRNA analytics that enable efficient monitoring of key upstream and downstream process steps will be showcased.