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Overview of Downstream Process of AAV Purification Using Monoliths and Rapid Evaluation of AAV Empty-Full Ratio with the PATfix™ HPLC System

Event: LCGC Live Webcast

Date: March 17, 2022

Presenters:  

Rok Zigon, Project Manager; Process Development Dept.

Blaz Goricar, Project Manager; Process Analytical Technology Dept.

Key learning points:

  • Rapid downstream process of AAV using monoliths, with emphasis on PATfix HPLC analytical tools
  • Orthogonal analytics are paramount for AAV characterization
  • Integration using PATfix enables fast evaluation of empty-full ratio