On May 12th, the biaseparations.com website will be retired and migrated tosartorius.com.Learn moreabout our combined offering today!

PATfix mRNA analytical platform

PATfix HPLC analytical system is all it takes to accelerate your process development and have continuous at-line production monitoring and robust quality control of nucleic acid drug substances. Designing a correct hardware setup for reproducible analytical separation of large biomolecules is not trivial. Complex IVT mixtures are composed of target molecule (mRNA), process-related impurities (nucleotides, capping reagent, DNA template) and product-related impurities (abortive fragments, dsRNA), all with similar biophysical characteristics. These challenges make the PATfix mRNA platform a preferred analytical solution