Quick Start methods for pDNA isoform monitoring with CIMac™ pDNA

CIMac™ pDNA Analytical Column is powerful tool for pDNA quantification for in-process control or in a QC laboratory. The column can separate pDNA isoforms from each-other and from RNA impurities. Monitoring of pDNA production leads to a controlled and robust process, and can result in consistent high quality of the final product.

Optimised methods are a key component of a well-functioning analytical system, sometimes requiring time-consuming method development and steep learning curves. The following two methods described in this quick start guide can provide a starting point for pDNA purity and isoform analysis.