CIMmultus™ stands for:
- Convective mass transfer, reduced backpressure, and minimal sample clogging
- Fast product isolation and concentration of diluted samples
- Efficient removal of high molecular mass impurities in polishing steps
CIMmultus™ C4 HLD-80 mL is an improved monolithic column with 2 μm pore size and a column volume of 80 mL. It is packed into an innovative epoxy-based housing and is supplied ready to use. CIMmultus™ C4 HLD-80 mL is intended for purifications at preparative and pilot scale. C4 HLD (high ligand - butyl) is a hydrophobic ligand, used in hydrophobic interaction chromatography (HIC). Due to high ligand density of butyl groups on the monolithic surface, it has proven to be excellent for:
- pDNA isoform separation
- Purification in an ammonium sulfate descending gradient
Due to highly hydrophobic nature of CIMmultus™ C4 HLD column separation/purification of proteins and peptides is only possible under the reversed phase conditions.