CIMac™ Analytical Columns are intended for fast and reproducible HPLC monitoring and quantitation of large proteins, plasmid DNA, viruses, virus-like particles, and phages. They were primarily designed for the in-process and final control of various samples at different stages of the purification process. They can be operated at high volumetric flow rates (from 1 to 20 column volumes/min); therefore, the information about the product quantity and purity can be obtained within a few minutes. CIMac™ Analytical Columns are fast and reliable PAT tools, providing:
- Rapid, high resolution analysis, achieved in minutes
- Flow independent separation
- High sensitivity and reproducibility
The CIMac™ EDA-0.1 Analytical Columns are weak anion-exchange monolithic columns, that bind biomolecules that are predominantly negatively charged over the pH working range of 3-9. In contrast to DEAE or QA monoliths it contains free primary amino groups, resulting in a promotion of not purely ion-exchange interaction.