CIM® OH-8f mL Tube Monolithic Column
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Cat. No.: 430.8140 |
General Description:
The CIM® OH-8f high throughput Tube Monolithic Column consists of a unique polymeric monolith encased in a specially designed housing. This column is used for extremely fast, highly efficient purification of large molecules such as proteins, DNA, viruses. The design of the column allows the mobile phase to run in a radial direction from the outer to the inner surface. In this way, resolution is preserved during scale-up while maintaining the short separation layer length. The short monolithic length and the specially engineered highly porous structure allow operations at elevated flow rates with low-pressure drops (only few bars).
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Features and Benefits:
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Extremely fast separations speed up method development and decrease costs. Speed also enables in-process control and analytics. |
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High binding capacity, even for large molecules, boost productivity even to 10-fold! |
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High flow rates can be achieved at moderate pressure drops- no need for expensive equipment (pumps) |
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Same material and design accross all sizes, enable easy scale-up from analytical, semi-prep and industrial scale. |
Dimensions and Operating Conditions:
Monolith dimensions
- Outer diameter, Do: 15.0 mm
- Inner diameter, Di: 6.5 mm
- Length, L: 56.0 mm
- Bed volume, V: 8.0 mL
Operating conditions
- flow rates: up to 400 mL/min (uav = 1340 cm/h)
- pressure: up to 20 bar (2 Mpa)
- temperature: 4 °C (39 °F) to 50 °C (122 °F)
- Recommended Ph:
working range 1–12
cleaning-in-place 1–14 (e. g. 1 M NaOH)
WARNING: Avoid prolonged use at elevated temperatures!
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