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Affinity

Affinity chromatography is based on the biospecific interaction between a biomolecule (commonly antibody) and its native or synthetic ligand. The effective ligands are immobilized on CIM® monoliths and associate with your antibodies in a highly specific and reversible manner. Association takes place at physiologic pH, while dissociation is most commonly effected by a pH shift. The strength of interaction strongly depends on the type of ligand and antibody. Affinity chromatography has become state of the art in antibody purification. We provide a selection of affinity monolithic columns for efficient purification of IgG and IgM.

  • IDA
  • IDA-Cu
  • n-Prot A
  • r-Prot A
  • r-Prot G
  • r-Prot L
  • Custom affinities