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In-Process Control of pDNA Production on CIMac™ pDNA Analytical Column

AN023-pDNA_CIMac pDNA_2010_1
AN023-pDNA_CIMac pDNA_2010_1AN023-pDNA_CIMac pDNA_2010_2

As the demand for plasmid DNA (pDNA) based gene therapy and vaccines increases, large scale, cost effective, and reproducible pDNA production will be required. The key to success is a real time in-process control method that ensures a high percentage of supercoiled pDNA in the final product. CIMac™ pDNA Analytical Column allows the monitoring of degradation products (open circular and linear pDNA), the removal of impurities (RNA), and ensures that each production step is yielding the amount of supercoiled pDNA anticipated.

CIMmultus™ HiP² Plasmid Process Pack™ 1-1 (1x DEAE 311.5114-2, 1x C4 HLD 311.8136-2)Information

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